About as regional as most other ITV news programmes .... I live on the edge of York, so I am forced to receive Tyne Tees (rather than Yorkshire Television that features news about where I actually live).
Since ITV closed the Border TV news gathering facility in Carlisle and transfered it to TT at Newcastle, we receive Border news too.
Given that Border covers SW Scotland, my 'local' sports news features articles about my local teams like Stranrear and Queen Of The South.