I generally find Warrington quite a scary place to go, the police presence for such a small catchment area is astounding. Or at least it used to be when I last went. Liverpool is a good night out and despite what reservations you may or may not have about the city, I think it's generally friendly too.

BTW, where is good in Manchester for a night out? I've been a few times now, and found it hit and miss.

Depends what you're into mate, South on a Saturday night is superb...Clint Boon from the Inspiral Carpets DJ'ing no undesirables in there either.